Frequently Asked Questions

What are the eligibility criteria for the Young Investigator program?

Young investigators at universities and research institutes in the United States and Canada with innovative projects and promising careers in pulmonary vascular disease are eligible. Click here for additional eligibility details

What is the length of the LOI submission sections?

The length of each LOI section should not exceed:
Introduction:  50 words
Background:  250 words
Hypothesis and Objectives:  50 words
Specific Aim 1, 2 and 3:  50 words per section (total maximum:  150 words)

What is meant by mentored career development?

This refers to the ways in which the young investigator (YI) and his/her mentor plan to support each other.  The mentor should be involved in overseeing the means for adequate funding to support necessary research, ensuring protected time for the YI to complete his/her research and to investigate career development, and helping the YI obtain a firm commitment from the YI's institution.

I will complete my current fellowship in June 2017 and have the option of extending it for another year under an NIH training grant (T32). As I will have completed my required fellowship term prior to the start of the next funding cycle, am I eligible to submit an LOI, even if I have a spot on an NIH T32 grant for 2017? Or do I need to wait until I have completed my time on the T32 prior to applying?

You must have completed your primary research training (PhD or sub-specialty fellowship training) by July 1st of the award year, and have a firm commitment from your home institution for mentored career development. If you believe that the proposed T32 training does not comprise primary training AND if you have the above-described institutional commitment, you should provide support of this in the LOI application.

Where does the ENTELLIGENCE Young Investigator Award Program get its grant funding?

ENTELLIGENCE was established by Actelion Pharmaceuticals US, Inc. in 2005. The ENTELLIGENCE Young Investigator Award Program provides individual grants of up to $100,000 each to qualified investigators to conduct research via a 12-month mentored grant. ENTELLIGENCE is an independent program funded by Actelion and managed by Medtelligence. Neither ENTELLIGENCE nor Medtelligence have not-for-profit status.

If I obtained my PhD in 2011 but I am still an Assistant Professor, am I eligible to apply for the 2017 ENTELLIGENCE Young Investigator award?

No.  The next funding cycle begins July 1, 2017, and thus you will be >5 years beyond your faculty appointment at the start of the award (as of July 1st of the award year).

If I have funding for a similar project, but that project does not specifically cover what my ENTELLIGENCE proposal covers, am I eligible to apply for the 2017 ENTELLIGENCE Young Investigator award?

It depends on how much overlap there is and also what your current funding level has been.  The ENTELLIGENCE Young Investigator Award program is not designed for PIs who have independent funding.  If the Steering Committee believes that you have already received funding to establish your career and/or are no longer considered a young investigator near the beginning of your career, they are not likely to consider your proposal to be competitive with other proposals.

I finished my last fellowship in 2012; however I have done several post-doc fellowships since earning my PhD degree in 2007. Am I eligible to apply for the 2017 ENTELLIGENCE Young Investigator Award?

Generally, although you will be <5 years out from fellowship, having completed multiple fellowships and your PhD degree 9 years ago, you would probably not be considered a young investigator.

I obtained my MD in 2008, completed residence in Surgery in 2013, and I am now a Clinical Instructor.  Am I eligible to apply for the 2017 ENTELLIGENCE Young Investigator Award?

Yes, you are <5 years out from training and at a rank less than Associate Professor, and thus you are considered a young investigator.

How do I begin the submission process?

Initially applicants should complete the Letter of Intent (LOI) form and submit the application with complete contact information through the online interface. Applications will not be considered if they are late, incomplete, or submitted by any means other than the provided Web site form. Click here for complete LOI guidelines, LOI form, and LOI Checklist.

Does the mentor need to be based at the same institution as the YI, or can I use a mentor who is based at another institution who I maintain close contact with?

Having a mentor based at a different institution as the YI is not strictly prohibited, but mentorship, career development, and academic/departmental support are important factors in considering merit for a YI award.

Can I return to the LOI form and/or Grant proposal on the Web site to make changes before official submission?

The LOI can be edited up until the LOI submission deadline, 11:59 pm [local time] November 3, 2016.  The Grant proposal can be edited until the Grant Submission deadline, 11:59 pm [local time] January 30, 2017.

How and when will I hear if my LOI was accepted?

After the LOI review ends, December 2, 2016, LOI applicants will be notified of acceptance or rejection via email. Accepted applicants will be sent an invitation to submit a full grant proposal. The email will provide detailed instructions for the grant proposal submission, as well as information on grant award agreements.  LOI applicants not selected will be notified via email accordingly.

 If my Letter of Intent (LOI) is not selected for full grant submission, may I reapply during a future grant cycle?

If you still meet the eligibility requirements, you may submit a proposal again in the future. Should you choose to apply again, please consider all of the eligibility and merit criteria carefully, particularly feasibility and eligibility. As noted elsewhere on the website, if the Steering Committee believes that you have already received funding to establish your career and/or are no longer considered a young investigator near the beginning of your career, they are not likely to consider your proposal to be competitive with other proposals. Thus, applicants who have had extended training, multiple degrees and/or multiple fellowships, current or prior research awards, or numerous publications may have their LOI rejected. In addition, if the project is not likely to be completed by the end of the 1-year funding period, the LOI may be rejected. Please review the rest of the frequently asked questions on this page, the Guidelines for LOI Submission, and the LOI Checklist.

Am I required to use a template for the grant proposal and budget?

Yes. Applicants should download the Grant Submission Form and the Budget/Budget Justification Form to their computer for completion. All completed applications must be uploaded to the grant application on the Web site and submitted in PDF format along with the documentation specified. Click here for complete guidelines and the Grant Submission Form and the Budget/Budget Justification Form.

If my LOI is accepted, what is the official deadline for final grant submission?

The final proposal must be submitted by January 30, 2017 at 11:59 PM [local time].

How can I expect to hear whether my grant proposal will be funded?

Applicants selected by the Steering Committee and those whose projects were not selected will be notified via email. Notification will be sent by March 20, 2017.

When must I submit progress reports and final reports?

Start of Research

Within 90 days following the award ceremony, an email supporting the start up of the research project, with complete documentation, should be sent to Jill Freeman, Program Director, at

Interim Progress Report

An Interim Progress Report must be submitted 6 months from the start up of the research project. The Interim Progress Report template must be downloaded to your computer to complete.  Once completed, the report must be uploaded to the ENTELLIGENCE Web site. Click here for the Interim Progress Report template.

Final Report

At the end of the grant period, a comprehensive final scientific report summarizing the project's accomplishments must be submitted to the ENTELLIGENCE Steering Committee. This report must include copies of any reprints, abstracts, and/or manuscripts submitted, published, or in press as a result of the research. Payment of the final grant installment is contingent upon approval of the final report by at least two Steering Committee members. All final reports must be submitted within 90 days of the termination date of the grant. Final reports are essential to the function of the award. Failure to submit final reports may affect eligibility for future funding. The completed report must be uploaded to the ENTELLIGENCE Web site. Click here for the Final Report template.

How will the funding be disbursed?

Funds allocated to each competition cycle will be distributed to successful applicants. Every project awarded will receive up to $100,000. The Steering Committee will decide the manner in which an award will be disbursed. The research project must be initiated within 90 days of the Awards Ceremony in which the grant term commences and funds are to be disbursed.

Award winners must submit all requested documentation. Funds are scheduled to be distributed in the following three installments:

  • • One-third (1/3) upon complete submission of paperwork (grant application agreement, IRB, W-9 Form from the institution, sample informed consent documents, if necessary, and IACUC, if necessary) and receipt of an invoice
  • • One-third (1/3) upon satisfactory receipt of an interim report and receipt of an invoice
  • • One-third (1/3) after completion of the research and upon satisfactory receipt of the final report and approval by at least two Steering Committee members and receipt of a final invoice.

Final reconciliation is required. If more than three installments will be paid, further progress reports may be requested before proceeding with payment.

Can I request an extension of my research project?

The ENTELLIGENCE Young Investigator Program is a 12-month mentored grant. If unforeseen circumstances lead to delays in completing the project in the specified timeframe, a request for additional project completion time must be submitted by the young investigator, mentor, and institution, explaining the reason(s) for the delay.  In addition, a plan for completing the project successfully within a newly specified timeframe must be provided and approved by the Steering Committee in order to receive funding.  Special consideration will be given by the Steering Committee to allow an additional period of time (maximum 12 months) to conduct research, but not to supply additional funding. Extensions will be considered on an individual basis only and are subject to final approval of the Steering Committee.

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